Endocrine Abstracts

Background: Hypothyroidism is characterised by insufficient secretion of the thyroid and its detection measured by elevated serum TSH levels.Although relatively common during pregnancy, untreated maternal hypothyroidism is associated with adverse obstetric and neonatal outcomes such as preeclampsia, placental abruption and miscarriage, or foetal neurodevelopment defects.Highlighting a nurse led specialised telephone clinic in the c...

Postural orthostatic tachycardia syndrome (PoTS) occurs as a consequence of the abnormal functioning of the autonomic nervous system (dysautonomia). Despite the many associated conditions, the assessment and relationship to reactive hypoglycaemia has not been explored in the clinical literature.The purpose of this retrospective observational-cohort study was to identify relationships between the physical and biochemical characteristics in potential carbo...

Introduction: Adolescents with persistent gender dysphoria (GD) receive GnRH analogues to achieve pubertal arrest. It is unclear whether this is adequate to achieve biochemical suppression of gonadotrophin (LH, FSH) and sex hormone production.Methods: Gonadotrophins, testosterone and oestradiol were measured in GD patients (15–18 years) before and after monthly Gonapeptyl treatment (3.75 mg i.m.). Patients administered other analogues and/or cross-s...